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丹參酮IIA

分析標準品,HPLC≥98%

Tanshinone IIA

CAS號：568-72-9

分子式：C19H18O3

分子量：294.34

MDL：MFCD00238692

產品介紹

熔點：205-207℃

沸點：480.7℃ at 760 mmHg

外觀：桔紅色針狀結晶

溶解性：按照順序添加:5%  DMSO+30%  PEG  300+2%  Tween  80+ddH2O。此方法可以溶解0.2mg/ml。丹參酮IIA溶液狀態下不穩定，需要現配現用，不能儲備液形式儲存。

儲存條件：2-8℃

注意：部分產品我司僅能提供部分信息，我司不保證所提供信息的權威性，僅供客戶參考交流研究之用。

參考文獻(106篇)

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83. [IF=2.8] Fang Liang et al."Therapeutic effects of Tanshinone IIA and Tetramethylpyrazine nanoemulsions on cognitive impairment and neuronal damage in Alzheimer’s disease rat models."JOURNAL OF PHARMACY AND PHARMACOLOGY.2024 Jun;:

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80. [IF=2.6] Fan Yang et al."Preliminary Exploration of Potential Active Ingredients and Molecular Mechanisms of Yanggan Yishui Granules for Treating Hypertensive Nephropathy Using UPLC-Q-TOF/MS Coupled with Network Pharmacology and Molecular Docking Strategy."Journal

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77. [IF=1.8] Meile Ma et al."Tanshinone IIA Regulates Synaptic Plasticity in Mg2+-Free-Induced Epileptic Hippocampal Neurons via the PI3K/Akt Signaling Pathway."Journal of Integrative Neuroscience".2024 Mar;23(3):61

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64. [IF=5.195] Jingwen Xu et al."Puerarin-Tanshinone IIA Suppresses atherosclerosis inflammatory plaque via targeting succinate/HIF-1α/IL-1β axis."JOURNAL OF ETHNOPHARMACOLOGY.2023 May;:116675

63. [IF=3.97] Xin Zhang et al."Nano-encapsulated tanshinone IIA in PLGA-PEG-COOH inhibits apoptosis and inflammation in cerebral ischemia/reperfusion injury."Green Processing and Synthesis.2023 Jan;12(1):

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31.  Miao-Juan Shi, Xiu-Li Yan, Ben-Sheng Dong, Wen-Na Yang, Shi-Bing Su, Hui Zhang,

A network pharmacology approach to investigating the mechanism of Tanshinone IIA for the treatment of liver fibrosis,

Journal of Ethnopharmacology,

Volume 253,

2020,

112689,

IS

30.  Li, Zhe, et al. "Folic acid modified lipid-bilayer coated mesoporous silica nanoparticles co-loading paclitaxel and tanshinone IIA for the treatment of acute promyelocytic leukemia." International Journal of Pharmaceutics 586 (2020): 119576.https:##doi.org

29.  Lu?btow, Michael M., et al. "Like dissolves like? A comprehensive evaluation of partial solubility parameters to predict polymer–drug compatibility in ultrahigh drug-loaded polymer micelles." Biomacromolecules 20.8 (2019): 3041-3056.https:##doi.org/10.1021

28.  Yang, Runyu, et al. "Limonin ameliorates acetaminophen-induced hepatotoxicity by activating Nrf2 antioxidative pathway and inhibiting NF-κB inflammatory response via upregulating Sirt1." Phytomedicine 69 (2020): 153211.https:##doi.org/10.1016/j.phymed.2020

27.  Ding, B., Lin, C., Liu, Q. et al. Tanshinone IIA attenuates neuroinflammation via inhibiting RAGE/NF-κB signaling pathway in vivo and in vitro. J Neuroinflammation 17, 302 (2020). https:##doi.org/10.1186/s12974-020-01981-4

26.  Li, Zhe, et al. "Biotinylated-lipid bilayer coated mesoporous silica nanoparticles for improving the bioavailability and anti-leukaemia activity of Tanshinone IIA." Artificial cells, nanomedicine, and biotechnology 46.sup1 (2018): 578-587.https:##doi.org/1

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